Control and Visualization

Control and Visualization

In order for micro- and nanorobots to be used safely in the human body one day, their movements must be precisely controllable and visible. Magnetic gradient fields can be used for control, exerting a force to navigate the robots to a specific point. In addition, rotating magnetic fields enable helical movement, and oscillating magnetic fields enable movement similar to that of a flagellum. Magnetic particle imaging (MPI) can be used for visualization. This technology enables the distribution of magnetic nanoparticles to be displayed in three dimensions with high temporal resolution and without radiation exposure. This not only allows continuous tracking of micro- and nanorobots, but also opens up new possibilities for medical diagnostics. For example, MPI can be used to measure temperature differences or changes in pH, allowing tissue conditions and disease progression to be monitored in real time. In our field of expertise, we investigate magnetic nanoparticles and drug carriers that can be visualized using MPI. One focus is on the further development of so-called multi-color MPI, which enables particles to be differentiated by color according to temperature, binding state, or material properties. This provides an even more detailed picture of biological processes, which not only enables more precise diagnoses but also creates the basis for individually tailored therapies.